Table 3. CNS depressant activity of different fraction of A. procera leaves by hole cross test in rats.
| Group | Mean hole cross (no.) before and after drug administration |
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| 0 min | 30 min | 60 min | 90 min | 120 min | |
| Control | 11.750±1.708 | 12.750±1.707 | 14.250±1.707 | 9.25±4.57 | 12.50±1.29 |
| Standard | 10.000±1.633 | 5.250±1.500 | 4.250±1.892b | 3.00±1.41a | 1.75±0.95b |
| EAF | 8.500±1.291a | 6.500±1.290a | 5.000±0.816b | 3.75±0.95a | 3.25±1.89b |
| CTCF | 9.750±1.708 | 5.500±1.291b | 6.500±1.290b | 3.75±1.70a | 2.25±2.06b |
| DCMF | 10.750±1.893 | 6.500±0.577b | 5.000±1.414b | 3.50±2.08a | 2.50±0.57 |
Values are presented as mean±SD. EAF: ethyl acetate fraction; DCMF: dichloromethane fraction; CTCF: carbon tetrachloride fraction; aP<0.05, bP<0.01 when compared to control.