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. 2014 Mar;21(3):161–170. doi: 10.1101/lm.032730.113

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© 2014 Sehgal et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date (see http://learnmem.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 4. — Long-delay fear conditioning reduces spike-frequency adaptation in a time-dependent manner. (A) Representative traces illustrating spike-frequency adaptation in response to a prolonged current injection. Note that LA pyramidal neurons from Control rats (n = 28) but not Cond-24hr rats (n = 28) display remarkable spike-frequency adaptation. Scale: 20 mV, 0.2 sec. (B) Average number of action potentials (APs) during prolonged current injection. LA pyramidal neurons from Cond-24hr rats fire significantly more APs than those from Control rats. Neurons from Cond-1hr rats (n = 13) are not significantly different from any other group. (*) P < 0.05 relative to LA neurons from Control rats.