Table 3. QLQ-C30, FAS and HADS mean scores for HL survivors vs norm population.
|
HL |
Norm |
|
||||
|---|---|---|---|---|---|---|
| Mean | s.d. | Mean | s.d. | P-value | Clinical relevance (Norman et al, 2003; Cocks et al, 2011) | |
|
QLQ-C30 | ||||||
|
Functional scales | ||||||
| Role functioning | 83.8 | 24.4 | 89.6 | 20.0 | 0.05 | Trivial |
| Physical functioning | 87.1 | 15.7 | 90.9 | 14.8 | 0.08 | Trivial |
| Cognitive functioning | 82.5 | 22.0 | 92.5 | 15.7 | <0.001 | Medium |
| Emotional functioning | 82.4 | 22.9 | 87.9 | 17.8 | 0.03 | Small |
| Social functioning |
86.4 |
22.2 |
92.8 |
17.6 |
<0.001 |
Small |
|
Symptom scales | ||||||
| Fatigue | 28.7 | 26.4 | 18.9 | 20.4 | <0.001 | Small |
| Pain | 13.0 | 22.4 | 14.2 | 20.9 | =0.54 | Trivial |
| Nausea/vomiting | 3.3 | 9.2 | 2.6 | 9.9 | =0.45 | Trivial |
| Global Health Status |
76.8 |
18.5 |
77.7 |
16.9 |
=0.57 |
Trivial |
|
FAS | ||||||
| Total fatigue score |
21.4 |
7.6 |
18.4 |
5.8 |
<0.001 |
Yes |
|
HADS | ||||||
| Anxiety mean scores | 4.7 | 4.2 | 3.8 | 4.3 | <0.001 | No |
| Anxiety mean score in fatigue cases | 7.6 | 4.5 | 6.5 | 4.0 | 0.31 | No |
| Depression mean scores | 3.7 | 3.8 | 3.4 | 3.2 | 0.02 | No |
| Depression mean score in fatigue cases | 6.6 | 4.1 | 6.4 | 4.0 | 0.83 | No |
Abbreviations: EORTC QLQ-C30=European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core-30; FAS=Fatigue Assessment Scale; HADS=Hospital Anxiety and Depression Scale; HL=Hodgkin's lymphoma.