Table 1. Relationship between ETBR expression and clinicopathological characteristics in oesophageal sequamous cell carcinoma.
| |
|
ETBR expression |
|
|
|---|---|---|---|---|
| Characteristics | Total (n=107) | High (n=61) | Low (n=46) | P-value |
|
Gender | ||||
| Male | 88 | 48 | 40 | 0.315 |
| Female |
19 |
13 |
6 |
|
| Age (years) (mean±s.d.) |
|
61.1±7.01 |
61.0±7.66 |
0.948 |
|
Diffrentiation | ||||
| Well | 39 | 16 | 23 | 0.013 |
| Moderate | 52 | 37 | 15 | |
| Poor |
16 |
8 |
8 |
|
|
Tumour depth | ||||
| pT1 | 23 | 9 | 14 | 0.041 |
| pT2 | 21 | 9 | 12 | |
| pT3 | 58 | 39 | 19 | |
|
pT4 |
5 |
4 |
1 |
|
|
Lymph node metastasis | ||||
| pN0 | 37 | 16 | 21 | 0.037 |
|
pN1 |
70 |
45 |
25 |
|
|
Distant metastasis | ||||
| M0 | 106 | 61 | 45 | 0.431 |
| M1 |
1 |
0 |
1 |
|
|
Lymphatic invasion | ||||
| Negative | 20 | 5 | 15 | 0.002 |
| Positive |
87 |
56 |
31 |
|
|
Venous invasion | ||||
| Negative | 60 | 28 | 32 | 0.019 |
| Positive |
47 |
33 |
14 |
|
|
Tumour stage | ||||
| I | 16 | 6 | 10 | 0.036 |
| II | 32 | 14 | 18 | |
| III | 42 | 29 | 13 | |
| IV |
17 |
12 |
5 |
|
| Tumour size (mm) (mean±s.d.) |
|
43.7±18.9 |
33.5±17.6 |
0.012 |
| Number of lymph node metastasis (mean±s.d.) | 4.94±7.15 | 1.90±3.40 | 0.016 | |