Table 3. Relationship between miRNA expression and DMFS in the confirmatory cohort of SCC patients, in the exploratory subset of stage I SCC from the confirmatory SCC cohort, and in AC patients.
| miRNA | All SCC P-value | All SCC FDR | All SCC Cox coefficients | Stage I SCC P-value | Stage I SCC FDR | Stage I SCC Cox coefficients | All AC P-value | All AC Cox coefficients |
|---|---|---|---|---|---|---|---|---|
| 662 |
<0.001 |
0.003 |
−0.22 |
<0.001 |
<0.001 |
−0.38 |
0.27 |
−0.102 |
| 192 |
0.002 |
0.007 |
−0.23 |
0.001 |
0.0044 |
−0.30 |
0.87 |
0.0118 |
| 192* |
0.017 |
0.034 |
−0.126 |
0.004 |
0.0088 |
−0.200 |
0.55 |
−0.042 |
| 502-3p |
0.057 |
0.085 |
0.106 |
0.043 |
0.065 |
0.142 |
0.125 |
0.111 |
| 128 |
0.106 |
0.128 |
0.104 |
0.068 |
0.082 |
0.143 |
0.90 |
0.0116 |
| 10b | 0.4 | 0.40 | −0.070 | 0.29 | 0.29 | −0.118 | 0.62 | −0.055 |
Abbreviations: AC=lung adenocarcinoma; DMFS=distant metastasis-free survival; SCC=squamous cell lung carcinoma.
Negative sign of Cox coefficient denotes that high miRNA expression correlates with shorter DMFS. Differences significant after Benjamini–Hochberg correction (FDR<0.05) are marked in bold.