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. 2014 Jan 7;110(4):908–915. doi: 10.1038/bjc.2013.812

Table 4. Hazard ratios for death (analysis from time of diagnosis).

Survival from diagnosis Total patients N=15 091 Deaths n=10 041 % HR 95% CI Adjusted HRa 95% CI
Townsend quintile
1 (Least deprived) 2111 1981 93.8 1.00   1.00  
2 2704 2558 94.6 1.02 0.96–1.08 1.03 0.98–1.10
3 2958 2788 94.3 1.02 0.96–1.08 1.01 0.95–1.07
4 3307 3109 94.0 1.01 0.95–1.06 1.03 0.98–1.09
5 (Most deprived) 3738 3517 94.1 0.99 0.94–1.05 1.02 0.96–1.08
Missing
273
262
96.0
1.69
1.49–1.93
1.39
1.22–1.58
Route of referral
Emergency admission 2323 2246 96.7 1.69 1.61–1.78 1.30 1.24–1.37
General Practitioner 7267 6738 92.7 1.00   1.00  
Consultant referral 2729 2566 94.0 1.19 1.14–1.25 1.01 0.96–1.06
Other (inc private) 887 836 94.3 1.18 1.10–1.27 1.03 0.96–1.11
Emergency Department 1120 1086 97.0 1.66 1.56–1.77 1.29 1.21–1.37
Missing
765
743
97.1
1.26
1.17–1.36
1.12
1.04–1.21
Radiotherapy
No chemotherapy 4509 4448 98.6 1.00   1.00  
Chemotherapy only 9590 8962 93.5 0.28 0.27–0.29 0.35 0.34–0.37
Chemo-radiotherapy
992
805
81.1
0.16
0.15–0.18
0.26
0.24–0.28
Chemotherapy cycles
No chemotherapy 4509 4448 98.6 1.00   1.00  
1–3 cycles 3228 3115 96.5 0.45 0.43–0.47 0.54 0.52–0.57
⩾4 cycles 5540 4936 89.1 0.20 0.19–0.21 0.25 0.24–0.27
NLCA record only
1814
1716
94.6
0.31
0.29–0.33
0.39
0.37–0.41
Time to treatment
<18 days 5137 4834 94.1 1.00   1.00  
⩾18 days 5445 4933 90.6 0.80 0.77–0.83 0.84 0.81–0.88
No chemotherapy
4509
4448
98.6
3.30
3.17–3.44
2.64
2.52–2.76
Trust first seen
Non-chemotherapy trust 4276 4011 93.8 1.00   1.00  
Chemotherapy trust 10 779 10 171 94.4 1.01 0.97–1.04 0.99 0.95–1.02
Missing/trust that saw <20 cases 36 33 91.7 0.99 0.70–1.39 0.93 0.66–1.32

Abbreviations: CI=confidence interval; HR=hazard ratio; NLCA=National Lung Cancer Audit.

a

Adjusted for sex, age, performance status, co-morbidity index and stage.