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. 2013 Dec 11;7:267. doi: 10.1186/1752-1947-7-267

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Copyright © 2013 Chang et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Histopathological findings of primary clear cell adenocarcinoma of the lung. Hematoxylin and eosin staining showed that the main tumor was infiltrated by pleomorphic clear tumor cells with foamy cytoplasm and distinct nucleoli ((A), 100×; (B) 400×). Positive immunohistochemical staining results included pancytokeratin AE1/AE3 (C), cytokeratin 7 (D), thyroid transcription factor 1 (E), Ki-67 (G), carcinoembryonic antigen (F) and periodic acid Schiff (H). Negative immunohistochemical stainings included HMB-45, Hep-par-1, transcription factor E3, α-inhibin, S-100 and CDX2 (data not shown).