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Schematic diagram of in vivo MR-guided LITT procedure in a canine model of brain. A 1.5-mm diameter water-cooled diffusing tip applicator was introduced percutaneously through the parietal bone. The applicator consisted of two clear, concentric tubes for water flow, the central of which contains an active 1-cm diffusing tip 400 μm diameter silica fibre-optic. Delivery of the photothermal energy is monitored using a multiplanar EPI sequence for MR temperature imaging.
