Table 1.
Demographic and clinical information for 22q11DS and control participants.
| 22q11DS participants (n = 16) |
Control participants (n = 25) |
p-Value | |
|---|---|---|---|
| Age (years, ± SD) | 23.88 (7.28) | 24.36 (6.14) | 0.83 |
| Participant education (years, ± SD) | 12.38 (0.89) | 14.36 (1.75) | < 0.001 |
| Parental education levela | 0/2/2/6/1/5 | 2/4/6/5/1/7 | 0.658 |
| Gender (N, % female) | 10 (63%) | 15 (60%) | 0.873 |
| Handedness (left/right, % right)b | 1/14 (93%) | 0/25 (100%) | 0.390 |
| Ethnicity (N, % Latino) | 2 (12.5%) | 9 (36%) | 0.098 |
| Psychotic disorder diagnosis (N, %) | 2 (12.5%) | None | < 0.001 |
| SIPS positive symptoms (mean, ± SD)c | 8.79 (7.54) | 0.75 (2.12) | < 0.001 |
| SIPS negative symptomsc | 11.43 (9.06) | 0.25 (0.46) | < 0.001 |
| SIPS disorganized symptomsc | 5.86 (4.74) | 1.25 (1.16) | < 0.001 |
| SIPS general symptomsc | 7 (5.14) | 1.5 (1.5) | < 0.001 |
| Psychotropic medication (N, no medication/anti-depressants/antipsychotics/antianxiety/psychostimulants)d | 7/8/2/3/5 | 24/1/0/0/0 | < 0.001 |
a
No high school/completed high school/some college or technical schools/completed college or technical school/some graduate school or professional school/completed graduate school or professional school (based on educational attainment of most educated parent).
b
Handedness data missing for 1 22q11DS participant.
c
SIPS data missing for 2 22q11DS participants; SIPS interview was not administered to 17 control participants, thus these data reflect scores for 8 control participants.
d
p-Value reflects a chi-square test between 22q11DS patients and control participants for medication vs. no medication.