Table 1.
Genotype and allele frequencies of C/T transition in single nucleotide polymorphism (SNP) (rs726252) of the PAPPA2 gene in Han Chinese population.
| Subjects | Number | Allele | Genotype | Hardy-Weinberg equilibrium P value | |||
|---|---|---|---|---|---|---|---|
| T (%) | C (%) | TT (%) | TC (%) | CC (%) | |||
| All cases | 697 | 1257 (90.2) | 137 (9.8) | 566 (81.2) | 125 (17.9) | 6 (0.9) | 0.754 |
| All controls | 707 | 1260 (89.1) | 154 (10.9) | 559 (79.1) | 142 (20.1) | 6 (0.8) | 0.355 |
| Female cases | 594 | 1074 (90.4) | 114 (9.6) | 485 (81.6) | 104 (17.5) | 5 (0.8) | 0.824 |
| Female controls | 299 | 535 (89.5) | 63 (10.5) | 237 (79.3) | 61 (20.4) | 1 (0.3) | 0.155 |
| Male cases | 103 | 183 (88.8) | 23 (11.2) | 81 (78.6) | 21 (20.4) | 1 (1.0) | 0.778 |
| Male controls | 408 | 725 (88.8) | 93 (11.2) | 322 (78.9) | 81 (19.9) | 5 (1.2) | 0.970 |