Model structural uncertainty: one-way sensitivity analysis of percentage of low-risk patients receiving abdominal CT. The base case analysis assumes that no low-risk patients in the CDR strategy receives an abdominal CT. However, in the real-world setting, clinicians may still obtain some abdominal CT scans in these patients. Here, we demonstrate that as more low-risk patients receive an abdominal CT, the incremental cost-effectiveness ratio decreases. At an abdominal CT scan proportion of 28.2%, the CDR strategy becomes dominated (more missed IAI and more costly) by the usual care strategy. CDR = clinical decision rule; IAI = intraabdominal injury requiring acute intervention; ICER = incremental cost-effectiveness ratio.