. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: J Tissue Viability. 2013 Jun 10;22(4):92–102. doi: 10.1016/j.jtv.2013.04.003

Table 3.

Summary of treatments for connective tissue ulcers

	Treatment

Rheumatoid arthritis	Pinch grafting Compression stockings when venous insufficiency present Adalimumab 40mg twice a month with Methotrexate 20mg weekly Topical tacrolimus Granulocyte monocyte adsorption

Scleroderma	Nifedipine Iloprost Warfarin Tretinoin Enzymatic debridement with occlusive dressing

Systemic lupus erythematosus	With vasculitis- systemic corticosteroids with cytotoxic agents (azathioprine or cyclophosphamide)

Sjogren’s Syndrome	Immunosuppressive agents

Dermatomyositis	Cyclophosphamide With Calcinosis – calcium channel blockers or colchicine

Mixed connective tissue disorder	Depends on etiology of ulcer