TABLE 2.
Representation of Functional Classes in Genes Exhibiting Changes in Expression Between PWS and Laser Treated Samples in Multiple Donors
Gene function | N vs. PWS UP | N vs. PWS DOWN | PWS vs. PWS + PDL UP | PWS vs. PWS + PDL DOWN |
---|---|---|---|---|
Epidermal | 4 | 1 | 3 | 0 |
Immune | 6 | 0 | 6 | 2 |
Lipid metabolism | 4 | 0 | 1 | 7 |
Signaling | 1 | 0 | 3 | 1 |
N, normal skin; PWS, port wine stain; PWS + PDL, port wine stain treated with pulsed dye laser; UP, up-regulated in PWS or PWS + PDL; DOWN, down-regulated in PWS or PWS + PDL.