Table 1:
Patient demographics, medical history and preoperative evaluation
| –PAF (n = 320) (%) | +PAF (n = 43) (%) | P-value | |
|---|---|---|---|
| Patient characteristics | |||
| Age | 0.01 | ||
| ≤69 | 205 (64) | 19 (44) | |
| ≥70 | 115 (36) | 24 (56) | |
| Sex | 0.45 | ||
| Male | 149 (47) | 19 (44) | |
| Female | 171 (53) | 24 (56) | |
| Body mass index median | 26.2 | 26.3 | 0.85 |
| Past medical history | |||
| Cardiac risk factors | |||
| Angioplasty/stents/angina | 22 (7) | 9 (21) | 0.01* |
| Myocardial infarction | 21 (7) | 4 (9) | 0.51 |
| Cerebrovascular disease | 16 (5) | 2 (5) | 0.64 |
| Peripheral vascular disease | 24 (8) | 2 (5) | 0.50 |
| Valvular disease | 15 (5) | 3 (7) | 0.52 |
| Other risk factors | |||
| Diabetes mellitus | 35 (11) | 7 (16) | 0.30 |
| Previous cancer | 125 (39) | 14 (33) | 0.41 |
| Previous cardiac surgery | 18 (6) | 4 (9) | 0.34 |
| Previous thoracic surgery | 17 (5) | 1 (2) | 0.40 |
| Preoperative chemotherapy | 7 (2) | 3 (7) | 0.07 |
| Preoperative radiation therapy | 3 (1) | 1 (2) | 0.41 |
| Lung function tests | |||
| FEV1 predicted, median, % | 82.0 | 82.5 | 0.70 |
| FVCpredicted, median, % | 89.0 | 83.0 | 0.21 |
| FEV1/FVC% | 70.0 | 69.0 | 0.51 |
| DLCOpredicted, median, % | 78.0 | 83.0 | 0.06 |
| Echocardiographic variables | (n = 258) | (n = 33) | |
| Left systolic dysfunction | 13 (5) | 6 (18) | <0.05* |
| Left diastolic dysfunction | 23 (9) | 6 (18) | 0.09 |
| Left atrial enlargement | 12 (5) | 3 (9) | 0.28 |
| Left ventricular hypertrophy | 6 (2) | 2 (6) | 0.2 |
| Pulmonary hypertension | 11 (4) | 1 (3) | 0.60 |
| Atrial septal defect | 3 (1) | 2 (6) | 0.04* |
| Valvular pathology | 23 (9) | 5 (15) | 0.25 |
| Diagnosis | 0.74 | ||
| Benign | 12 (8) | 1 (2) | |
| Malignant NSCLC | 244 (76) | 35 (81) | |
| Other malignant | 64 (20) | 7 (16) | |
% DLCO: diffusing capacity of the lung for carbon monoxide; % NSCLC: non-small-cell lung cancer.