Table 1.
Mast cell mediators
| Biogenic amines |
| Biogenic amines [histamine (2–5 pg/cell), serotonin] |
| Cytokines |
| Interleukins 1–6 |
| Leukaemia inhibitory factor |
| Tumour necrosis factor-α |
| Interferon-γ |
| Transforming growth factor-β |
| Granulocyte–macrophage colony-stimulating factor |
| Enzymes |
| Acid hydrolases |
| Chymase |
| Phospholipases |
| Rat mast-cell protease I and II |
| Trypase |
| Lipid metabolites |
| Prostaglandin D2 |
| Leukotriene C4 |
| Platelet-activating factor |
| Other bioactive molecules |
| Neuropeptides (e.g. vasoactive intestinal peptide, substance P) |
| Proteoglycans, mainly heparin (active as an anticoagulant) |
| Nerve growth factor |
| ATP |
| Nitric oxide |