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Induction of apoptosis by the candidate compounds. (A) TUNEL assay demonstrating the induction of apoptosis in CHP134 cells. Concentrations of candidate compounds are 5 μmol/L for compounds A and G. Cells were incubated for 3 days prior to TUNEL reaction. DAPI (blue), TUNEL signal (red), and merged images were shown for molecules A and G, respectively. (B) Immunoblotting shows the induction of apoptosis in CHP134 cells. Actin is a loading control.
