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Overall survival according to status of disease after the 45th day of epidermal growth factor receptor tyrosine-kinase inhibitors treatment (n = 227 patients). PD, progressive disease; CD, controlled disease. Kaplan–Meier method (P < 0.0001) and the log-rank test. Controlled disease group: median of 385 days, 95% CI [267–481], 1st–3rd quartiles [169–776]; PD group: median of 77 days, 95% CI [61–109], 1st–3rd quartiles [41–195].
