Figure 1.

Immunohistochemistry (IHC) for ADAM12, FAP, WISP1, and SOX11 in areas of more “active” cells (left column) and less “active” cells (right column). In regions of “active” cells ADAM12 staining was primarily nuclear and cytoplasmic; FAP staining was primarily cytoplasmic; WISP1 was cytoplasmic; and SOX11 was primarily nuclear.