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. Author manuscript; available in PMC: 2014 Feb 20.
Published in final edited form as: J Theor Biol. 2012 Jul 20;311:117–129. doi: 10.1016/j.jtbi.2012.07.007

Figure 3.

Figure 3

Simplification of acyclic to cyclic chain. (a) Full scheme with three high occupancy states, A, B, and C and one low occupancy state, t. (b) Simplified three state scheme after aggregation. (c) An example of modified “Y” chain where there are direct links between high occupancy states in addition to the links through low occupancy state. jMN and kMN stand for the flux parameter and transition rate between states M and N respectively. JMN(dir) in panel (c) represents the direct flux between high occupancy states M and N.