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. 2014 Feb 11;7:111–117. doi: 10.2147/JMDH.S38616

Table 1.

Level of evidence

Rating Strength of evidence
A Results of a meta-analysis or multiple randomized controlled trials (RCTs) on humans.
B Results of one VLU-related RCT in humans plus one or more similar historically controlled trials (HCT) or convenience controlled trials (CCT). May include two significant clinical series or expert opinion papers with literature reviews supporting the intervention.
C Results of only one RCT, CCT, or HCT. May include multiple case series.

Note: Modified from the Advancement of Wound Care (AAWC), Venous Ulcer Guideline Level of Evidence and Wound Healing Society Level of Evidence.3,4