Table 4. Overexpression of sup-18 in body-wall muscles enhances the defects of sup-10(n983gf) but not unc-93(e1500gf) mutants.
Genotype | LR ± SEM | Brood size |
Wild-type | 26.8±0.4 | ND |
lin-15; nEx[lin-15(+)#1] | 26.5±0.9 | ND |
lin-15; nEx[lin-15(+)#2] | 27.3±0.7 | ND |
lin-15; nEx[lin-15(+); sup-18(+)#1] | 27.1±0.8 | ND |
lin-15; nEx[lin-15(+); sup-18(+)#2] | 26.9±0.8 | ND |
lin-15; nEx[lin-15(+); sup-10(+); sup-18(+)#1] | 24.5±0.8 | ND |
lin-15; nEx[lin-15(+); sup-10(+); sup-18(+)#2] | 25.2±0.8 | ND |
sup-10(n983gf) lin-15; nEx[lin-15(+)#1] | 5.7±0.4 | 74±5 |
sup-10(n983gf) lin-15; nEx[lin-15(+)#2] | 5.4±0.4 | 75±4 |
sup-10(n983gf) lin-15; nEx[lin-15(+); sup-18(+)#1] | 0.1±0.1 | 27±3 |
sup-10(n983gf) lin-15; nEx[lin-15(+); sup-18(+)#2] | 0.0±0.0 | 17±3 |
sup-10(n983gf) lin-15; nEx[lin-15(+); sup-10(n983gf)#1] | 5.9±1.2 | ND |
sup-10(n983gf) lin-15; nEx[lin-15(+); sup-10(n983gf)#2] | 6.6±0.8 | ND |
sup-10(n983gf) lin-15; nEx[lin-15(+); sup-9(+)#1] | 6.0±0.6 | ND |
sup-10(n983gf) lin-15; nEx[lin-15(+); sup-9(+)#2] | 5.1±0.4 | ND |
sup-10(n983gf) lin-15; nEx[lin-15(+); unc-93(+)#1] | 5.1±0.3 | ND |
sup-10(n983gf) lin-15; nEx[lin-15(+); unc-93(+)#2] | 5.8±0.5 | ND |
unc-93(e1500gf); lin-15; nEx[lin-15(+)#1] | 0.0±0.0 | 35±2 |
unc-93(e1500gf); lin-15; nEx[lin-15(+)#2] | 0.0±0.0 | 43±2 |
unc-93(e1500gf); lin-15; nEx[lin-15(+); sup-18(+)#1] | 0.0±0.0 | 37±2 |
unc-93(e1500gf); lin-15; nEx[lin-15(+); sup-18(+)#2] | 0.0±0.0 | 40±3 |
sup-9(n1550gf); sup-18(n1030) | 0.0±0.0 | 24±1 |
Locomotion rate, mean for 12 animals. Brood size, mean for 10 animals. Four extrachromosomal arrays (nEx) were generated, two containing lin-15(+) alone and two containing both lin-15(+) and sup-18(+), and were introduced into the different genetic backgrounds by mating to ensure consistent gene dosage among experiments. ND, not determined. LR: locomotory rate (bodybends/min).