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. 2014 Feb 20;8(2):e2679. doi: 10.1371/journal.pntd.0002679

Figure 2. Lack of dermal residing MF does not alter filarial-specific antibody profiles.

Figure 2

Plasma samples from all participants (NEN, MF+ and a-MF) were investigated for the presence of filarial-specific Igs by ELISA. Plates were coated overnight with 5 µg/ml O. volvulus worm extract. Thereafter, levels of IgE (A) and IgG4 (B) were detected in all individual samples diluted 1∶20 and 1∶500 respectively. Data are depicted as absolute values expressed in arbitrary units [AU]. Graphs show box whiskers with median, interquartile ranges and outliers. Statistical significances between the indicated groups were obtained after Kruskal-Wallis and Mann-Whitney tests. Data in (C) show the correlation of dermal MF with the amount of filarial-specific IgG4; determined using the Spearman correlation test.