Table 2. Allelic heterogeneity at the AGXT2 locus.

Locus		CoLaus							TasteSensomics
Chr	Position	Feature	SNP	PC	xC	R2	R2diff	model P	Feature	SNP	PT	xT	R2	R2diff	model P
5	34,537,671–35,578,717	1.2025	rs37370	2.1×10−37	0.95	0.278	0.079	2.0×10−4	1.204	rs37370	2.2×10−21	0.92	0.130	0.047	2.0×10−4
			rs7717823	1.1×10−20	−0.47					rs455423	5.9×10−8	−0.41
			rs6880595	5.1×10−4	0.18
5	34,537,671–35,578,717	3.0975	rs37369	3.6×10−16	0.78	0.115	0.023	2.2×10−3	3.096	rs37370	6.6×10−12	0.68	0.097	0.026	6.2×10−3
			rs7717823	3.5×10−6	−0.25					rs455423	1.0×10−4	−0.31

Abbreviations: P_C, P_T – P-values, x_C, x_T – multivariate effect sizes, R² – explained variance of full model, R²_diff – additional explained variance of full model compared to best single SNP association, model P – probability of observing same or equal R²_diff increase with the same stepwise model selection for 2,500 permuted phenotypes.