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. 2014 Feb 20;8(2):e2698. doi: 10.1371/journal.pntd.0002698

Table 1. Single and multiple drug dosages evaluated in vivo against mature adults of T. muris, classified by route of administration.

Dosage (mg/kg) 0.5 1.0 2.5 5.0 7.5 10 15 20 25 50 75 100 150 200 250 300 400 500
PF1022A 3×oral X X X X X X X X
1× oral X X X X X X X X
3× subcutaneous X X X X X X X X
3× intraperitoneal X X X X X X X X
Emodepside 3× oral X X X X X X X X
3× subcutaneous X X X X X X X X
3× intraperitoneal X X X X X X X X
Amidantel 3× oral X
3× subcutaneous
3× intraperitoneal
dAMD 3× oral X X X X X X
3× subcutaneous X X
3× intraperitoneal X X X X X
Tribendimidine 3× oral X X X X X X
3× subcutaneous X X
3× intraperitoneal X X X X X

‘X’ indicated that the respective drug was evaluated in the given dose using the indicated route of administration.