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. 2014 Feb 20;10(2):e1004162. doi: 10.1371/journal.pgen.1004162

Figure 6. Model of genome-wide expression effects caused by X-17 interaction.

Figure 6

A musculus PWD allele on the X @15 cM interacts with heterozygous 17@13 cM (likely Prdm9) to cause overexpression of the X chromosome during meiosis. X-linked transcriptional regulation genes, which are usually silenced by MSCI, affect expression of autosomal genes.