Figure 3. Effect of a single MS on colonic and ileal permeability to FD4 and intact HRP in PND10 rats.

Ussing chambers measurements of mucosal-to-serosal permeability to Dextran 4 kDa and HRP 44 kDa in (A) colonic and (B) ileal segments of PND10 pups immediately after MS (T4 h). Note that MS increased FD4 and intact HRP permeability in the colon, but not in the ileum. Pooled data of both genders are shown and are expressed as the mean of permeability to FD4 (cm/s x10⁻⁶)±SEM in 9–16 animals per group, and HRP (cm/s × 10⁻⁷)±SEM in 6–17 animals per group. *P<0.05 **P<0.01 compared to corresponding sham controls.