Table 3.
Summary of cumulative 42-day release and aggregation behavior of lysozyme from implants prepared from various polymers with or without 3% MgCO3.
| Polymer Name | Lysozyme (%) | MgCO3 (%) | Cumulative Release (%) | Soluble Residue (%) | Insoluble Aggregates (%) | Recovery (%) |
|---|---|---|---|---|---|---|
| AB10 | 15 | 0 | 85 ± 1 | 0.5 ± 0.1 | 7.9 ± 0.4 | 94 ± 1 |
| AB10 | 15 | 3 | 100 ± 1 | 0.1 ± 0.1 | 4.8 ± 0.6 | 105 ± 1 |
| AB15 | 15 | 0 | 99 ± 2 | 0 | 1.9 ± 0.5 | 101 ± 2 |
| AB15 | 15 | 3 | 104 ± 2 | 0 | 2.0 ± 0.3 | 106 ± 3 |
| ABA10 | 15 | 0 | 88 ± 1 | 0 | 6.8 ± 0.2 | 95 ± 1 |
| ABA10 | 15 | 3 | 85 ± 1 | 0 | 2.8 ± 0.1 | 88 ± 1 |
| PLGA | 15 | 0 | 80 ± 2 | 0.5 ± 0.1 | 13.2 ± 0.2 | 94 ± 2 |
| PLGA | 15 | 3 | 67 ± 4 | 12 ± 3 | 20.3 ± 0.9 | 100 ± 4 |