Table 3.
Site stratified proportional hazards models with multiple predictors of frailty characteristics for depressed and nondepressed men and women.
| Nondepressed (n=543) |
Depressed (n=261) |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Men (n=278) |
Women (n=265) |
Men (n=84) |
Women (n=177) |
|||||||||
| Frailty Predictors | Wald χ2 |
Hazard ratio (95% CI) |
p Value |
Wald χ2 |
Hazard ratio (95% CI) |
p Value |
Wald χ2 |
Hazard ratio (95% CI) |
p Value |
Wald χ2 |
Hazard ratio (95% CI) |
p Value |
| Low Physical Activities | 10.48 | 0.005 | 1.25 | 0.535 | 1.81 | 0.404 | 3.66 | 0.160 | ||||
| Yes vs. No | 7.27 | 1.76 (1.17, 2.65) | 0.007 | 1.13 | 1.34 (0.78, 2.28) | 0.287 | 1.61 | 1.68 (0.76, 3.74) | 0.204 | 2.86 | 1.56 (0.93, 2.61) | 0.091 |
| Missing vs. No | 4.85 | 2.80 (1.12, 7.01) | 0.028 | 0.01 | 0.95 (0.36, 2.50) | 0.917 | 0.09 | 1.25 (0.29, 5.46) | 0.765 | 0.19 | 0.81 (0.32, 2.05) | 0.662 |
| Fatigue | 4.90 | 0.086 | 3.67 | 0.160 | 6.46 | 0.040 | 5.62 | 0.060 | ||||
| Yes vs. No | 3.82 | 1.51 (1.00, 2.28) | 0.051 | 2.73 | 1.54 (0.92, 2.56) | 0.098 | 1.02 | 1.48 (0.69, 3.15) | 0.313 | 5.40 | 1.94 (1.11, 3.40) | 0.020 |
| Missing vs. No | 2.24 | 1.46 (0.89, 2.41) | 0.134 | 1.96 | 1.52 (0.85, 2.74) | 0.161 | 6.29 | 2.90 (1.26, 6.67) | 0.012 | 2.81 | 1.66 (0.92, 3.00) | 0.094 |
| Slow Gait Speed | 5.99 | 0.050 | 1.89 | 0.388 | 2.17 | 0.338 | 6.69 | 0.035 | ||||
| Yes vs. No | 4.96 | 1.54 (1.05, 2.26) | 0.026 | 1.04 | 1.30 (0.79, 2.14) | 0.307 | 1.01 | 1.52 (0.67, 3.45) | 0.315 | 4.59 | 1.84 (1.05, 3.21) | 0.032 |
| Missing vs. No | 1.92 | 1.71 (0.80, 3.64) | 0.166 | 1.38 | 1.85 (0.66, 5.18) | 0.240 | 1.95 | 2.67 (0.67, 10.59) | 0.163 | 5.47 | 2.71 (1.18, 6.26) | 0.019 |
| Low Grip Strength | 2.34 | 0.310 | 4.92 | 0.085 | 0.64 | 0.725 | 1.60 | 0.452 | ||||
| Yes vs. No | 0.01 | 1.02 (0.65, 1.59) | 0.934 | 4.64 | 1.83 (1.06, 3.18) | 0.031 | 0.63 | 1.35 (0.64, 2.81) | 0.429 | 0.43 | 1.19 (0.70, 2.02) | 0.513 |
| Missing vs. No | 2.19 | 0.55 (0.25, 1.22) | 0.139 | 0.85 | 1.52 (0.63, 3.69) | 0.355 | 0.05 | 1.15 (0.33, 4.02) | 0.827 | 1.46 | 1.59 (0.75, 3.36) | 0.228 |
Cox proportional hazard models were used to explore the simultaneous effects of the baseline frailty characteristics in separate models for nondepressed and depressed men and women. Wald χ2 values are listed; (df = 2 for the overall effect of each frailty characteristic, df= 1 for each subgroup comparison); Hazard ratios (and 95% CI) are for multiple predictor models with the inclusion of other frailty characteristics as covariates.