Table 1. Characteristics of eligible studies in this meta-analysis.
| Author | Year | Ethnicity | Cancer type | Controls source | Case | Control | Genotyping method |
| rs2066842 C/T (P268S) | |||||||
| Roberts, R. L. | 2006 | New Zealander | Colorectal cancer | PB | 133 | 201 | ARMS |
| Wex, T. | 2008 | German | Gastric cancer | PB | 167 | 153 | PCR-RFLP |
| Szeliga, J. | 2008 | Polish | Rectal cancer | HB | 51 | 100 | PCR-RFLP |
| Hnatyszyn, A. | 2010 | Polish | Gastric cancer | HB | 17 | 113 | Pyrosequencing |
| rs2066844 C/T (R702W) | |||||||
| Debniak, T. | 2005 | Polish | Melanoma | HB | 470 | 649 | Allele-specific PCR |
| Papaconstantinou, I. | 2005 | Greek | Colorectal cancer | N.A. | 104 | 100 | Allele-specific PCR |
| Rosenstiel, P. | 2006 | German | Gastric MALT lymphoma | HB | 83 | 308 | Taqman |
| Roberts, R. L. | 2006 | New Zealander | Colorectal cancer | PB | 133 | 201 | ARMS |
| Lakatos, P. L. | 2007 | Hungarian | Colorectal cancer | N.A. | 194 | 200 | dHPLC |
| Vogel, U. | 2007 | Danish | Colorectal cancer | PB | 355 | 753 | CE-SSCP |
| Tuupanen, S. | 2007 | Finnish | Colorectal cancer | PB | 953 | 508 | ARMS |
| Szeliga, J. | 2008 | Polish | Rectal cancer | HB | 51 | 100 | PCR-RFLP |
| Suchy, J. | 2008 | Polish | Colorectal cancer | HB | 350 | 350 | PCR-RFLP |
| Ture-Ozdemir, F. | 2008 | Greek | Gastric MALT lymphoma | HB | 56 | 51 | PCR-RFLP |
| Wex, T. | 2008 | German | Gastric cancer | PB | 159 | 150 | PCR-RFLP |
| Mockelmann, N. | 2009 | German | Colorectal cancer | PB | 1044 | 724 | SNPlex |
| Angeletti, S. | 2009 | Italian | Gastric cancer | PB | 170 | 156 | PCR-ARMS |
| Freire, P. | 2010 | Portuguese | Colorectal cancer | PB | 112 | 152 | Real-time PCR |
| Rigoli, L. | 2010 | Italian | Gastric cancer | PB | 60 | 87 | PCR-RFLP |
| Ashton, K. A. | 2010 | Austrilian | Endometrial cancer | PB | 213 | 291 | Real-time PCR |
| rs2066845 C/G (G908R) | |||||||
| Papaconstantinou, I. | 2005 | Greek | Colorectal cancer | N.A. | 104 | 100 | PCR-RFLP |
| Debniak, T. | 2005 | Polish | Melanoma | HB | 470 | 649 | Allele-specific PCR |
| Rosenstiel, P. | 2006 | German | Gastric MALT lymphoma | HB | 83 | 308 | Taqman |
| Roberts, R. L. | 2006 | New Zealander | Colorectal cancer | PB | 133 | 201 | ARMS |
| Tuupanen, S. | 2007 | Finnish | Colorectal cancer | PB | 960 | 508 | ARMS |
| Lakatos, P. L. | 2007 | Hungarian | Colorectal cancer | N.A. | 194 | 200 | dHPLC |
| Vogel, U. | 2007 | Danish | Colorectal cancer | PB | 355 | 753 | CE-SSCP |
| Ture-Ozdemir, F. | 2008 | Greek | Gastric MALT lymphoma | HB | 56 | 51 | PCR-RFLP |
| Szeliga, J. | 2008 | Polish | Rectal cancer | HB | 51 | 100 | PCR-RFLP |
| Suchy, J. | 2008 | Polish | Colorectal cancer | HB | 350 | 350 | PCR-RFLP |
| Mockelmann, N. | 2009 | German | Colorectal cancer | PB | 1044 | 724 | SNPlex |
| Freire, P. | 2010 | Portuguese | Colorectal cancer | PB | 112 | 152 | Real-time PCR |
| Rigoli, L. | 2010 | Italian | Gastric cancer | PB | 60 | 87 | PCR-RFLP |
| Ashton, K. A. | 2010 | Austrilian | Endometrial cancer | PB | 213 | 291 | Real-time PCR |
| rs2066847/rs5743293 (3020insC) | |||||||
| Nej, K. | 2004 | Polish | Pancreatic cancer | HB | 127 | 300 | Allele-specific PCR |
| Kurzawski, G. | 2004 | Polish | Colorectal cancer | HB | 556 | 300 | Allele-specific PCR |
| Alhopuro, P. | 2004 | Finnish | Colorectal cancer | PB | 926 | 348 | Allele-specific PCR |
| Huzarski, T. | 2005 | Polish | Breast cancer | HB | 462 | 1910 | Allele-specific PCR |
| Debniak, T. | 2005 | Polish | Melanoma | HB | 470 | 649 | Allele-specific PCR |
| Lubinski, J. | 2005 | Polish | Mixed | HB | 2850 | 1910 | Allele-specific PCR |
| Papaconstantinou, I. | 2005 | Greek | Colorectal cancer | N.A. | 104 | 100 | Allele-specific PCR |
| Rothman, N. | 2006 | Caucasian | Non-Hodgkin lymphoma | PB/HB | 3069 | 3497 | Mixed |
| Forrest, M. S. | 2006 | British, American | Non-Hodgkin lymphoma | PB | 899 | 1433 | Taqman |
| Roberts, R. L. | 2006 | New Zealander | Colorectal cancer | PB | 133 | 201 | ARMS |
| Jaworowska, E. | 2006 | Polish | Laryngeal cancer | HB | 347 | 4102 | Allele-specific PCR |
| Irmejs, A. | 2006 | Latvian | Mixed | PB | 420 | 974 | Allele-specific PCR |
| Lener, M. R. | 2006 | Polish | Mixed | HB | 4496 | 2068 | Allele-specific PCR |
| Lakatos, P. L. | 2007 | Hungarian | Colorectal cancer | N.A. | 194 | 200 | dHPLC |
| Vogel, U. | 2007 | Danish | Colorectal cancer | PB | 355 | 753 | CE-SSCP |
| Ennas, M. G. | 2008 | Italian | Lymphocytic leukaemia | PB | 39 | 109 | Taqman |
| Magnowski, P. | 2008 | Polish | Ovarian cancer | HB | 257 | 1910 | Allele-specific PCR |
| Szeliga, J. | 2008 | Polish | Rectal cancer | HB | 51 | 100 | ASA |
| Suchy, J. | 2008 | Polish | Colorectal cancer | HB | 607 | 607 | PCR-RFLP |
| Wex, T. | 2008 | German | Gastric cancer | PB | 47 | 48 | PCR-RFLP |
| Ture-Ozdemir, F. | 2008 | Greek | Gastric MALT lymphoma | HB | 56 | 51 | PCR-RFLP |
| Angeletti, S. | 2009 | Italian | Gastric cancer | PB | 170 | 156 | Multiplex PCR |
| Rigoli, L. | 2010 | Italian | Gastric cancer | PB | 60 | 87 | PCR-RFLP |
| Skibola, C. F. | 2010 | Mixed | Non-Hodgkin lymphoma | PB/HB | 6360 | 6636 | Mixed |
| Freire, P. | 2010 | Portuguese | Colorectal cancer | PB | 112 | 152 | Real-time PCR |
Abbreviations: PB: population-based; HB: hospital-based.