Figure 4. Pressure-volume loops, cardiac output, end-diastolic pressure and stroke work.

Typical pressure-volume loops obtained by conductance catheter from a sham operated non-pregnant rat (full line) and a pregnant rat with transverse aortic constriction (dotted line) (A). Mean±SEM for calculated cardiac output (B), end-diastolic pressure (C) and calculated stroke work (D). Comparisons between groups were made using one-way ANOVA and Holm-Sidak post hoc test. NP, non-pregnant, TAC, transverse aorta constriction. p<0.05 compared to non-pregnant sham (*), non-pregnant TAC (†), or pregnant sham rats (‡).