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. 2014 Feb 20;9(2):e89553. doi: 10.1371/journal.pone.0089553

Figure 4. TGFβ induces migration in p53 null cells in comparison to p53 wild-type or mutant cells.

Figure 4

(a) Wound healing assays were performed on SKOV3 and OVCA 420 stable cell lines. Cell monolayers were scratched and treated with or without TGFβ at 20 ng/mL for 48 hours. Wound closure was measured as a fold increase or decrease compared to no treatment control. Paired t-test was used with a p≤0.05. (b) Comparison of the fold increase of TGFβ samples from 5(a). Unpaired t-test was used to analyze significance. Significance is represented by * and signifies a statistical difference between cell lines. Data represented as mean ± SEM, *p≤0.05.