Skip to main content
. 2014 Feb 21;4:22. doi: 10.3389/fcimb.2014.00022

Table 2.

MHC-I and MHC-II binding force predictions for LLO and GAPDH epitopes.

MHC-I binding MHC-I allele Percentile rank Sequence
LLO91−99 H-2-Kd 1.8* Complete (GB)
H-2-Ld 38.3
H-2-Kb 75.1
GAPDH1−22 H-2-Kb 1.6* 5–15*
H-2-Ld 2.3 8–18
H-2-Kd 4.7 8–16
MHC-II binding MHC-II allele Percentile rank Sequence
LLO190−201 H-2-IAb 74.3* Complete (WB)
GAPDH1−22 H-2-IAb 69.15* 4–18*
H-2-IAb 70.23 5–19
H-2-IAb 70.91 2–16
H-2-IAb 71.11 3–17
H-2-IAb 74.95* 8–22*
H-2-IAb 75.61 7–21
H-2-IAb 75.72 1–15

Predictions of binding of peptides to MHC molecules performed with the IEDB analysis source Consensus tool. The lower the percentile ranks obtained, the better the binders. GAPDH1-22 peptide was compared to the predictions of LLO91-99 binding to MHC-I molecules and LLO189-201 binding to MHC-II molecules.

*

Comparative peptide sequence with similar binding percentiles as LLO peptides. GB, good binder; WB, weak binder.