Table 2.
MHC-I binding | MHC-I allele | Percentile rank | Sequence |
---|---|---|---|
LLO91−99 | H-2-Kd | 1.8* | Complete (GB) |
H-2-Ld | 38.3 | ||
H-2-Kb | 75.1 | ||
GAPDH1−22 | H-2-Kb | 1.6* | 5–15* |
H-2-Ld | 2.3 | 8–18 | |
H-2-Kd | 4.7 | 8–16 | |
MHC-II binding | MHC-II allele | Percentile rank | Sequence |
LLO190−201 | H-2-IAb | 74.3* | Complete (WB) |
GAPDH1−22 | H-2-IAb | 69.15* | 4–18* |
H-2-IAb | 70.23 | 5–19 | |
H-2-IAb | 70.91 | 2–16 | |
H-2-IAb | 71.11 | 3–17 | |
H-2-IAb | 74.95* | 8–22* | |
H-2-IAb | 75.61 | 7–21 | |
H-2-IAb | 75.72 | 1–15 |
Predictions of binding of peptides to MHC molecules performed with the IEDB analysis source Consensus tool. The lower the percentile ranks obtained, the better the binders. GAPDH1-22 peptide was compared to the predictions of LLO91-99 binding to MHC-I molecules and LLO189-201 binding to MHC-II molecules.
Comparative peptide sequence with similar binding percentiles as LLO peptides. GB, good binder; WB, weak binder.