Fig. 2.

Baseline and week 48 mean SF-36 domain scores in ALLEVIATE.

Spydergrams showing baseline and week 48 mean SF-36 domain scores vs age- and gender-matched norms for (A) placebo (n = 36 and n = 14, respectively), (B) epratuzumab 360 mg/m² (n = 40 and n = 14) and (C) epratuzumab 720 mg/m² (n = 10 and n = 4) in ALLEVIATE. Inner polygon (light blue) indicates baseline domain scores, outer polygon (yellow) indicates age- and gender-matched norms and intermediate polygon (dark blue) indicates mean changes at week 48. Physical domains are presented clockwise from the top and mental domains clockwise from the bottom. Physical domains are: PFI: physical function; ROLP: physical role; PAIN: bodily pain; GHP: general health. Mental domains are: VITAL: vitality; SOC: social function; ROLE: emotional role; MHI: mental health.