Table 2. Genotypes of SMARCA4 rs11879293 and the association with risk of HCC in both stages.
| Stage 1 | Stage 2 | Combined | ||||
|---|---|---|---|---|---|---|
| Variables | Cases/controls | OR (95% CI)‡ | Cases/controls | OR (95% CI)‡ | Cases/controls | OR (95% CI)‡ |
| SMARCA4 rs11879293 | ||||||
| GG | 263/209 | Reference | 251/251 | Reference | 514/460 | Reference |
| AG | 191/202 | 0.72 (0.54–0.95) | 205/226 | 0.92 (0.70–1.21) | 396/428 | 0.80 (0.63–1.00) |
| AA | 48/70 | 0.51 (0.33–0.78) | 32/67 | 0.50 (0.31–0.82) | 80/137 | 0.49 (0.33–0.72) |
| AG+AA | 239/272 | 0.66 (0.51–0.86) | 237/293 | 0.83 (0.64–1.08) | 476/565 | 0.72 (0.58–0.90) |
| Additive model | 0.72(0.59–0.87) | 0.79 (0.64–0.96) | 0.73 (0.62–0.87) | |||
‡ORs and 95% CIs were calculated by unconditional logistic regression after adjusting for sex, age, smoking, drinking and HBsAg.