Figure 5. Serial EM cross-sections of C-LTMR and Aδ-LTMR axonal endings at a zigzag hair follicle.
Serial EM cross-sections spanning more than 3 µm along two different LTMR axonal terminals of lanceolate complex at a zigzag hair follicle were collected. Representative images that are approximately 0.4 μm to 0.5 μm apart were shown. (A) A1 to A8 are serial EM cross-sections of an axonal terminal that has a relatively small number of mitochondria with low electron density. Further analyses (Figure 6, Figure 6—figure supplement 2) show that this axonal ending type is likely to be C-LTMR. (B) B1 to B8 are serial EM cross-sections of an axonal terminal that is packed with mitochondria with relatively high electron density. Further analyses (Figure 6, Figure 6—figure supplement 2) show that this axonal ending type is likely to be Aδ-LTMR. Animals around 4 weeks of age were used for these experiments. Scale bar, 500 nm.