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. Author manuscript; available in PMC: 2014 Aug 26.
Published in final edited form as: Organometallics. 2013 Aug 26;32(16):4656–4663. doi: 10.1021/om400630q

Table 2.

Kumada coupling of 4-chloroanisole and o-tolylmagnesium chloride employing various nickel(II) precatalysts.

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Entry Catalyst Yield
1 3 92
2 4 89
3 5 90
4 6 87
5 11 82
6 12 82
7 13 84
8 14 91

Conditions: 1.0 mmol 4-chloroanisole; 1.3 mmol o-tolyl Grignard; 3 mL toluene; 12 h. Yields reported for isolated product.