TABLE 1.

Summary of iPSC immunogenicity data reported in four recent studies

+, immune rejection reported; −, minimal or no immune rejection reported; NT, not tested.

Syngeneic cells injected	Zhao et al. (9)a	Araki et al. (10)a	Guha et al. (11)b	Morizane et al. (12)c
Undifferentiated iPSCs	+	+	−	NT
Undifferentiated ESCs	−	+	−	NT
In vivo differentiated iPSCs	NT	−	NT	NT
In vitro differentiated iPSCs	NT	+	−	−

^a All cells were injected subcutaneously.

^b All cells were injected into the subcapsular renal space.

^c All cells were injected into the brain (putamen).