FIGURE 7.

Effect of FOS, FOSB, and FOSL1 shRNAs on tube formation by trophoblast cells. Swan 71 trophoblast cells expressing control shRNA (shCTRL) or shRNAs for FOS, FOSB, or FOSL1 were placed in Matrigel-coated plates, and representative images taken at 24 or 48 h are shown in A. The white arrows in bottom shFOS panel identify cells migrating away from the tube formations. B, the total number of tubes formed at 24 h was scored. Values significantly different (p < 0.05) from controls are denoted with an asterisk (*). Error bars represent S.E.