TABLE 1.

Kinetic parameters for WT and mutated LTC4S against GSH and LTA₄

	kcat	Km	kcat/Km
	s−1	μm	m−1/s−1
WT-GSH	12 ± 0.7	300.0 ± 60	4 ± 1.1 × 104
W116F-GSH	17.7 ± 1.3	2380 ± 440.0	0.7 ± 0.07 × 104
W116A-GSH	16.8 ± 1.2	1420 ± 290.0	1.1 ± 0.1 × 104
WT-LTA4	26 ± 4	30.0 ± 10	8.7 ± 4 × 105
W116F-LTA4	74.3 ± 12.5	94.6 ± 29.4	7.3 ± 0.8 × 105
W116A-LTA4	32 ± 2.7	37.9 ± 8.69	8.1 ± 0.98 × 105