Figure 4.

Ultrashort echo time (UTE)-MRI of the lungs. Coronal T1-weighted UTE images of mice from each cohort in this study: (A) BM mouse + collagen-targeted EP-3533; (B) sham mouse + EP-3533; (C) BM + control probe EP-3612; (D) sham + EP-3612. False color overlay is the difference image obtained by subtracting the UTE image acquired before probe injection from the UTE image taken after probe injection. Mice with pulmonary fibrosis that receive the collagen-specific probe (A) show much higher pulmonary signal enhancement than sham mice or mice receiving the control probe. All images rendered at the same scale.