Table 1. Overview of previous LA and LDLA methods.
| Paper | Model | Data needed | Experimental design | Estimation | 1 locus/multilocus | IBD matrix |
|---|---|---|---|---|---|---|
| Meuwissen and Goddard (2004) | LDLA | Haplotypes No. of generations Effective population size | General pedigree | Bayes MCMC | Multilocus | Yes |
| Lund et al. (2003) | LDLA | Haplotypes | Granddaughter design | Classic ML | 1 or 2 locus | Yes |
| Fulker et al. (1999) | LDLA/TDT | Dense map of diallelic markers Sib-pairs with parental genotypes | Sib-pair | Classic | 1 locus | No |
| George et al. (1999) | TDT | Pedigree | General pedigree | Classic | 1 locus | No |
| Hernández-Sánchez et al. (2009) | LDLA | Genotypes/haplotypes Pedigree No. of generations Effective populationsize | Any population structure | Classic | 1 locus | Yes |
| Pérez-Enciso (2003) | LDLA | Haplotypes Pedigree | General pedigree | Bayes MCMC | 1 locus | No |
| Abecasis et al. (2000b) | TDT | Genotypes | Pedigree | Classic | 1 locus | No |
| Farnir et al. (2002) | LDLA | Haplotypes | Half sib | Classic EM | 1 locus | No |
| Göring and Terwilliger (2000) | LDLA | Genotypes | Any population structure | Classic | 1 locus | No |
| Lee and Van der Werf (2006) | LDLA | Haplotypes | General pedigree | Empirical Bayes/stochastic EM | Multilocus | Yes |
| Yi and Xu (2000) | LA | Genotypes | General pedigree | Bayes | Multilocus | Yes |
| George et al. (2000) | LA | Genotypes | General pedigree | Classic | 1 locus | Yes |
| Lange et al. (2013) | LDLA | Pedigree | General pedigree | Classic | 1 locus | No |
Abbreviations: LDLA, linkage disequilibrium linkage analysis; MCMC, Markov Chain Monte Carlo methods; TDT, transmission disequilibrium test.