Table 1.
Baseline characteristics of subjects by treatment assignment
| Esomeprazole (n = 9) | Placebo (n = 8) | p value | |
|---|---|---|---|
| Reflux present on pH probe |
5/8 (62%) |
3/5 (60%) |
0.42 |
| Male (%) |
67 |
75 |
0.38 |
| Pseudomonas present (%) |
89 |
62 |
|
| MRSA present(%) |
0 |
25 |
|
| |
Mean + SD |
Mean + SD |
|
| Age (years) |
35.72 + 9.6 |
32.81 + 5.84 |
0.41 |
| BMI |
24.25 + 4.72 |
21.84 + 3.02 |
0.21 |
| # exacerbations past 2 years |
4 + 0 (0) |
5.5 + 1.4 (SD) |
|
| FEV1 (%) |
58 + 19 |
46 + 21 |
0.14 |
| FVC (%) |
74 + 20 |
71 + 16 |
0.88 |
| FEV1/FVC |
0.63 + 0.10 |
0.56 + 0.15 |
0.26 |
| GSAS distress score |
0.99 + 0.61 |
0.88 + 1.03 |
0.28 |
| CFR-QOL score | 72.28 + 10.32 | 77.85 + 18.86 | 0.34 |