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. Author manuscript; available in PMC: 2015 Jan 7.
Published in final edited form as: Cell Metab. 2013 Dec 26;19(1):162–171. doi: 10.1016/j.cmet.2013.11.017

Figure 2. Obesity increases macrophage proliferation specifically in adipose tissue.

Figure 2

See also Figure S2. WT and ob/ob mice were i.p. injected with EdU and (A) AT, (B) spleen, (C) liver and (D) blood were collected and digested 3 hours after treatment. All cells were stained and analyzed by flow cytometry. Representative dot plots depict the EdU incorporation into all cells of the respective tissues or blood monocytes. (E) Mean percentage of EdU incorporation rate of the macrophages of each tissue ± s.e.m. (F) Percentage of macrophages in each tissue. n= 14-15 from 3 independent experiments for AT and blood, and n=9-10 from 2 independent experiments for spleen and liver. Statistical significance was determined by Student’s t-test. ***p<0.001.