Table 2. Scope of Asymmetric Nitro-Mannich Reaction of Ketiminesa.


Reactions were carried out on 0.2 mmol of 5 at the indicated temperature.
Enantiomeric excess (ee) was determined by HPLC analysis on a chiral stationary phase. *Conversion was 50%.


Reactions were carried out on 0.2 mmol of 5 at the indicated temperature.
Enantiomeric excess (ee) was determined by HPLC analysis on a chiral stationary phase. *Conversion was 50%.