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Association Between PLCE1 Genotypes and Esophagitis in High- and Low-Risk Areas of China
| High-incidence area % (n) |
Low-incidence area % (n) |
|||||
|---|---|---|---|---|---|---|
| Genotypes | AA | AG/GG | OR (95% CI) | AA | AG/GG | OR (95% CI) |
| Mild esophagitis | 86% (126) | 80% (76) | 1.00 | 92% (296) | 91% (230) | 1.00 |
| Moderate | 12% (18) | 9% (9) | 0.84 (0.36–1.97) | 3% (10) | 5% (13) | 1.67 (0.72–3.89) |
| Severe | 2% (3) | 11% (10) | 6.03 (1.59–22.9)* | 5% (17) | 4% (10) | 0.73 (0.33–1.64) |
OR, odds ratio; CI, confidence interval.
P = 0.008.
