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. Author manuscript; available in PMC: 2014 Feb 21.
Published in final edited form as: Mol Cell. 2011 Mar 4;41(5):579–588. doi: 10.1016/j.molcel.2011.02.012

Figure 6. Model for N1 exon repression by PTB.

Figure 6

Binding of PTB to the CU rich elements flanking the N1 exon allow its interaction with SL4 of U1 snRNA. This prevents U1 from interacting with the complex at the downstream 3′ splice site.