TABLE IVB.

Association of Prostate Cancer (PCa) Diagnosis and Grade with Smoking in African Americans

African Americans	PCa casese versus control unadjusted OR (95% CI)	PCa casesa versus control adjusted OR (95% CI)		Low-grade PCa (n = 141) versus controlsd OR (95% CI)	High-grade PCa (n = 119) versus controlsf OR (95% CI)
Smoking categories			Smoking categories
Never smokers & <20 cigarettes/day	1.00 (reference)	1.00 (reference)	Never smokers	1.00 (reference)	1.00 (reference)
≥20 cigarettes/day	1.80 (1.22, 2.65)c	2.57 (1.09, 6.10)d	<20 cigarettes/day	1.36 (0.84, 2.21)	1.21 (0.69, 2.13)
			≥20 cigarettes/day	1.15 (0.63, 2.11)	1.89 (1.03, 3.48)d
PCa family history			Married
Negative	1.00 (reference)	1.00 (reference)	No	1.00 (reference)	1.00 (reference)
Positive	1.21 (0.82, 1.79)	1.63 (0.83, 3.22)	Yes	0.84 (0.53, 1.33)c	0.77 (0.46, 1.29)
Age	1.08 (1.06, 1.10)c	1.08 (1.04, 1.12)c	Alcohol use
Obesity			<2 drinks/day	1.00 (reference)	1.00 (reference)
BMI <30	1.00 (reference)	1.00 (reference)	≥2 drinks/day	2.24 (1.18, 4.25)d	1.40 (0.65, 3.00)
BMI ≥30	0.60 (0.41, 0.88)c	0.87 (0.46, 1.64)
High school education
Yes	1.00 (reference)	1.00 (reference)
No	3.63 (1.94, 6.79)c	3.04 (1.35, 6.84)c

Table IV B the best unconditional logistic regression model adjusted for known prostate cancer risk factors is presented based on −2 log likelihood scores. Income, 5 alpha-reductase inhibitor use, and city of recruitment failed to reach statistical significance in the analyses and did not improve −2 log likelihood scores and were excluded.

BMI: Body Mass Index

CI: Confidence Interval

PCa: Prostate Cancer

^aP < 0.05.

^bP < 0.01.

^cN = 422 for AA controls/N = 400 for EA.

^dN for AA controls = 400.