Table 1. Characteristics of Study Subjects at Baseline.
TRC150094 (N = 20) | Placebo (N = 20) | |
Age, y | 49±11 | 50±10 |
Weight, kg | 102±18 | 103±19 |
Body mass index, kg/m2 | 33.3±4.5 | 33.6±4.9 |
Waist, cm | 112.5±12.0 | 114.7±11.8 |
Systolic blood pressure, mm Hg | 140±8 | 137±10 |
Diastolic blood pressure, mm Hg | 88±4 | 87±7 |
Fasting plasma glucose, mmol/L | 5.6±1.0 | 5.3±0.6 |
Fasting plasma insulin, mU/L | 12±7 | 14±8 |
HOMA-IR | 2.9±1.8 | 3.5±2.4 |
EGP suppr, % | 60±16 | 67±15 |
Rd, µmol kg −1 min −1 | 29±7 | 28±6 |
Fasting free fatty acids, mmol/L | 0.51±0.10 | 0.52±0.19 |
Cholesterol, mmol/L | 4.63±1.03 | 4.90±0.74 |
HDLc | 0.94±0.24 | 1.01±0.32 |
LDLc | 2.91±0.82 | 3.13±0.71 |
TG | 1.60±1.06 | 1.67±0.72 |
NOTE. Values are expressed as mean ± standard deviation. No significant differences in clinical variables were found between TRC and Placebo group at baseline, p<0.05. The body mass index is the weight in kilograms divided by the square of the height in meters. HDLc, high-density lipoprotein cholesterol; LDLc, low-density lipoprotein cholesterol; TG, triglycerides.