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. 2014 Feb 21;9(2):e85214. doi: 10.1371/journal.pone.0085214

Table 6. Association of AKI stages with BUN and SCr levels.

Stage
Stage I Stage II Stage III P value*
First abnormality
BUN (mmol/l) 11.1 (8.1–15.5) 15.2 (10.9–22.5) 24.8 (16.9–33.8) <0.0001
SCr (µmol/l) 148.1 (132.0–178.0) 260.2 (237.1–305.1) 536.3 (381.1–804.0) <0.0001
Peak
BUN (mmol/l) 23.9 (14.6–34.1) 24.2 (15.4–33.4) 31.0 (22.8–40.6) <0.0001
SCr (µmol/l) 290.0 (203.6–399.9) 392.6 (267.5–543.2) 670.7 (488.7–917.8) <0.0001
Discharge
BUN (mmol/l) 12.5 (7.3–29.0) 18.5 (7.6–26.8) 15.8 (8.4–25.9) 0.65
SCr (µmol/l) 185.0 (101.0–323.0) 244.6 (106.0–440.1) 299.0 (135.1–540.0) 0.001

These biological parameters were measured using an automatic biochemistry analyzer (Hitachi 76000, Japan).

*P for trend among AKI stage I to III.

BUN at first abnormality: H = 71.42 (rank sum test); BUN at peak: H = 19.19 (rank sum test); BUN at discharge: H = 0.85 (rank sum test); SCr at first abnormality: H = 169.62 (rank sum test); SCr at peak: H = 114.82 (rank sum test); SCr at discharge: H = 14.41, (rank sum test).