Table 3. Association of serum NAb titres with diagnosis (PD patients versus Controls).
Part A | |||
PD | Controls | p-value | |
Abeta1–42 NAb (OD) | 8.43 (0–11) | 8.58 (0–10.98) | 0.75 |
Asyn NAb | 6.73 (0–9.46) | 6.46 (0–10.80) | 0.50 |
MBP NAb | 7.76 (0–10.29) | 7.94 (0–10.72) | 0.98 |
MOG NAb | 0 (0–8.86) | 0 (0–9.51) | 0.25 |
S100B NAb | 8.01 (0–11.08) | 8.11 (0–11.40) | 0.46 |
Logarithmized serum NAb titres were calculated using a multiple linear regression model with age, gender (PD versus controls) as covariates. Data are presented with median (range). P-values <0.025 (0.05/2) were considered significant. Abeta1–42, Amyloid-beta1–42; Asyn, Alpha-synuclein; MBP, Myelin basic protein; MOG, Myelin oligodendrocyte glycoprotein; NAb, naturally occurring autoantibody; OD, Optical density; PD, Parkinson’s disease; S100B, S100 calcium binding protein B.